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目的:了解流感流行趋势及毒株变化情况,为制定流感防控策略提供科学依据。方法:利用实时荧光PCR法对流感监测标本进行流感病毒核酸检测,阳性标本进行病毒分离。结果:804份标本检出流感病毒核酸阳性168份;分离流感毒株57株。2010年流感高峰期发生在8月,以季甲H3型为优势毒株;2011年流感高峰期出现1月-3月,以新甲H1N1为优势毒株。流感患病率无性别差异,以5～年龄组流感病毒阳性率最高。结论:2010年-2011年万州区流感流行分别以季节性H3N2型、B-victoria系和新甲H1N1型为优势毒株。预防流感流行的重点人群是在校期间的中小学生。
OBJECTIVE: To understand the epidemic trend of flu and the change of strains, and to provide a scientific basis for the development of influenza prevention and control strategies. Methods: The influenza virus nucleic acid was detected by real-time fluorescence PCR and the positive samples were isolated by virus. Results: A total of 168 influenza virus nucleic acid positive samples were detected in 804 samples and 57 influenza virus isolates were isolated. Influenza peak in 2010 occurred in August, with the season of H3 strain as the dominant strain; peak influenza in 2011 appeared in January-March, with the new strain of H1N1 strain. Influenza prevalence rate of non-sex differences in 5 ~ age group the highest positive rate of influenza virus. Conclusion: From 2010 to 2011, the prevalence of influenza in Wanzhou district was seasonal H3N2, B-victoria and XNX1 respectively. The key population to prevent the epidemic is primary and secondary school students.