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目的观察云贵高原地区哮喘—慢性阻塞性肺疾病重叠综合征(ACOS)患者42例临床特征。方法收集2014年7月-2016年4月该院呼吸与危重症医学科经肺功能检测确诊的ACOS患者42例(即ACOS组)和43例单纯慢性阻塞性肺疾病(COPD)患者(即单纯慢阻肺组)的临床资料,比较2组FEV1/FVC比例、FEV1/预计值比例、人均住院费用及人均住院天数。结果 2组患者人均住院天数差异无统计学意义(P>0.05);ACOS组FEV1/FVC、FEV1/预计值均低于单纯慢阻肺组,人均住院费用高于单纯慢阻肺组,差异均有统计学意义(P<0.05)。结论云贵高原地区ACOS患者较单纯慢阻肺患者呼吸道气流受限更重,临床治疗费用更高,ACOS成为制约云贵高原地区居民健康水平及经济水平的一种重要疾病。
Objective To observe the clinical features of 42 patients with asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) in the Yunnan-Guizhou Plateau. Methods Forty-two patients with ACOS (ACOS group) and 43 patients with chronic obstructive pulmonary disease (COPD) diagnosed by pulmonary function test from July 2014 to April 2016 in the Department of Respiratory and Critical Care Medicine, COPD). The FEV1 / FVC ratio, FEV1 / predicted ratio, per capita hospitalization cost and per capita hospitalization days were compared between the two groups. Results There was no significant difference in hospitalization days between the two groups (P> 0.05). The FEV1 / FVC and FEV1 / predicted FEV1 / FVC in ACOS group were lower than those in simple COPD group There was statistical significance (P <0.05). Conclusion The ACOS patients in the Yunnan-Guizhou Plateau are more restrictive than the patients with chronic obstructive pulmonary disease and the treatment costs are higher. ACOS has become an important disease that restricts the health and economic level of residents in the Yunnan-Guizhou Plateau.