男性酒精摄入量与血清HDL-C水平的量效关系

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目的分析男性酒精摄入量与血清高密度脂蛋白胆固醇(HDL-C)水平的量效关系。方法采用问卷调查结合血脂检测的方法,对758例只有饮用白酒习惯的男性,分析其酒精摄入量与HDL-C水平的相关性,并计算回归方程,对相关系数与回归系数进行统计学检验。结果男性日均摄入80g以内酒精者,酒精摄入量与血清HDL-C水平呈正相关,相关系数r=0.104(P<0.005);直线回归方程为Y=1.2348+0.0019x(回归系数检验,P<0.001)。男性日均摄入80g以上酒精者,酒精摄入量与血清HDL-C水平无相关性(P>0.05)。结论男性每日饮用酒精量在80g之内时,HDL-C水平随酒精摄入量增加而增加;随着酒精量的继续增加,这种量效关系则消失。建议男性酒精摄入量应控制在80g/d之内。 Objective To analyze the dose-response relationship between male alcohol intake and serum high-density lipoprotein cholesterol (HDL-C) levels. Methods A total of 758 males with drinking habits were analyzed by questionnaire and serum lipids. The correlation between alcohol intake and HDL-C level was analyzed. The regression equation was calculated and the correlation coefficient and regression coefficient were statistically tested . Results Male daily intake of alcohol within 80g, alcohol intake and serum HDL-C levels were positively correlated, the correlation coefficient r = 0.104 (P <0.005); linear regression equation was Y = 1.2348 + 0.0019x (regression coefficient test, P <0.001). Male daily intake of more than 80g alcohol, alcohol intake and serum HDL-C levels had no correlation (P> 0.05). Conclusions When the daily drinking amount of alcohol in men is less than 80g, the level of HDL-C increases with the increase of alcohol intake. As the amount of alcohol continues to increase, the dose-effect relationship disappears. Proposed male alcohol intake should be controlled within 80g / d.
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