目的:观察中西医结合治疗中青年肝郁脾虚型不寐患者的临床疗效。方法:纳入92例中青年肝郁脾虚型不寐患者,随机分为治疗组和对照组各46例。治疗组给予疏肝补脾汤联合艾司唑仑片治疗,对照组仅予艾司唑仑片治疗。治疗时间均为2月。在治疗前、治疗1月及治疗2月分别采用匹兹堡睡眠质量指数(PSQI)对2组患者进行睡眠质量的评价。比较2组的临床疗效。结果:治疗后,治疗组总有效率78.26%,对照组总有效率56.52%,2组比较,差异有统计学意义(P<0.05)。治疗组治疗1月、2月后的PSQI均较治疗前降低,治疗2月的PSQI较治疗1月亦有所降低,差异均有统计学意义(P<0.05)。对照组治疗前后的PSQI比较,差异均无统计学意义(P>0.05)。治疗1月、2月,2组PSQI比较,差异均有统计学意义(P<0.05)。结论:疏肝补脾汤联合艾司唑仑片治疗中青年肝郁脾虚型不寐患者可提高睡眠质量,疗效优于单纯服用艾司唑仑片。 Objective: To observe the clinical efficacy of traditional Chinese and western medicine in the treatment of middle-aged and young stagnation patients with spleen-deficiency syndrome. Methods: Ninety-two middle-aged and young patients with liver-qi deficiency syndrome were randomly divided into treatment group (46 cases) and control group (46 cases). The treatment group was treated with Shuganxuepi Decoction combined with estazolam tablets, while the control group only with estazolam tablets. Treatment time is February. Before treatment, January and February treatment Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the quality of sleep in two groups. Compare the clinical efficacy of the two groups. Results: After treatment, the total effective rate was 78.26% in the treatment group and 56.52% in the control group. There was significant difference between the two groups (P <0.05). The PSQI of the treatment group after 1 and 2 months of treatment was lower than that before the treatment, and the PSQI of the treatment group was also lower than that of the January of treatment in the treatment group. The difference was statistically significant (P <0.05). There was no significant difference in PSQI between before and after treatment in control group (P> 0.05). There was significant difference between the two groups in the treatment of PSQI in January, February and February (P <0.05). Conclusion: Shugan Bupi Decoction combined with estazolam tablets can improve sleep quality in patients with middle-aged and young patients with spleen-deficiency syndrome of stagnation of liver-qi and stagnation of spleen, and its curative effect is better than that of simply taking eszolam tablets.