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目的:探讨喹诺酮类药物临床不良反应及其安全性用药。方法:选取2015年6月至2016年6月在我院就诊的135例使用喹诺酮类药物患者,统计药物所造成的临床不良反应观察指标,分析引起喹诺酮类药物不良反应的影响因素,并提出合理的安全用药建议。结果:135例患者共发生不良反应14处,累及部位有皮肤、消化道、全身性反应、神经系统、肝功能、肾功能。结论:使用喹诺酮类药物可发生不良反应,临床医护人员选用喹诺酮类药物时要慎重选择,避免不良反应的发生,提高用药安全性。
Objective: To investigate the clinical adverse effects of quinolones and their safety. Methods: From June 2015 to June 2016, 135 patients treated with quinolones in our hospital were enrolled in this study. The clinical adverse reactions caused by the drugs were statistically analyzed, and the influencing factors of the adverse reactions of quinolones were analyzed and put forward reasonable Safe medication recommendations. Results: A total of 135 adverse reactions occurred in 135 patients with skin, digestive tract, systemic reaction, nervous system, liver function and renal function. Conclusions: Adverse reactions can occur with quinolones. Clinologists should choose carefully quinolones to avoid adverse reactions and improve the safety of medication.