论文部分内容阅读
目的了解南京市男男性行为者(MSM)Rush poppers(简称Rush)的使用情况,并分析在无保护肛交和多性伴的背景下,Rush的使用与HIV/梅毒感染的关系。方法 2014年11月至2015年2月、2015年4-7月,分别在南京市开展2轮横断面调查,招募MSM参加匿名问卷调查和血清学检测,调查内容主要包括社会人口学特征、性角色、近6个月性行为情况和Rush使用情况等。采用多因素Logistic回归模型评估控制了性伴数目和无保护肛交后,Rush的使用与HIV/梅毒感染的关系。结果1 040名MSM中,23.7%的MSM近6个月使用过Rush,48.8%的MSM近6个月有≥2同性性伴,42.9%的MSM近6个月与同性性伴发生过无保护肛交。MSM的HIV和梅毒感染率分别为11.9%和6.1%。Rush的使用和HIV感染呈正相关[调整比值比(aOR)=2.127,95%可信区间(CI):1.402~3.225],Rush使用者近6个月更有可能有≥2个同性性伴(aOR=3.818,95%CI:2.754~5.294),更有可能发生无保护肛交(aOR=1.765,95%CI:1.310~2.376)。控制了无保护肛交的影响后,Rush使用和HIV感染仍呈正相关(aOR=1.955,95%CI:1.283~2.981)。结论南京市MSM中Rush使用和无保护肛交在预测HIV感染风险中共同起着重要的作用,Rush等新型毒品的使用也应成为MSM社区参与宣传教育关注的重点。
Objective To understand the use of Rush poppers (MSRs) in Nanjing and to analyze the relationship between Rush use and HIV / syphilis infection in the context of unprotected anal intercourse and polygamy. Methods From November 2014 to February 2015 and April-July 2015, two rounds of cross-sectional surveys were conducted in Nanjing, MSM was recruited to participate in anonymous questionnaires and serological tests. The survey mainly included the socio-demographic characteristics, sex Role, nearly six months of sexual behavior and Rush usage. Multivariate Logistic regression models were used to assess the relationship between the use of Rush and HIV / syphilis infection after controlling the number of sexual partners and unprotected anal sex. Results Among 1040 MSMs, 23.7% of MSM used Rush in the past 6 months, 48.8% of MSM had ≥2 same-sex partners in the past 6 months, 42.9% of MSM had no protection with same-sex partners in nearly 6 months Anal sex. HIV and syphilis infection rates for MSM were 11.9% and 6.1%, respectively. Rush use was positively correlated with HIV infection (adjusted odds ratio (aOR) = 2.127, 95% confidence interval (CI): 1.402 to 3.225] and Rush users were more likely to have> 2 homosexual partners in the nearly 6 months aOR = 3.818, 95% CI: 2.754-5.294), and more likely unprotected anal intercourse (aOR = 1.765, 95% CI: 1.310-2.376). After controlling for the effects of unprotected anal intercourse, there was a positive correlation between Rush use and HIV infection (aOR = 1.955, 95% CI: 1.283-2.981). Conclusion Rush use and unprotected anal intercourse in Nanjing MSM play an important role in predicting the risk of HIV infection. The use of new drugs such as Rush should also be the focus of MSM community’s participation in publicity and education.