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目的 为了对肝前型门脉高压症的术式选择提供依据。方法 应用缩窄门静脉方法进行动物(犬) 的肝前型门脉高压症的模型制作。将已形成肝前型门脉高压症犬18 只分为4 组,分别进行脾切除术、脾切除+ 贲门周围血管离断术、肠腔分流术及联合手术。手术前后测定门脉压力进行对比。结果 与术前相比,脾切除有一定降低门脉压的作用(P< 0.05);肠腔分流术降压效果最佳( P<0.001) ;脾切除+ 离断术无明显降压作用;联合手术降压效果亦佳( P< 0.01) ,而肠腔分流术与联合手术相比降压效果无显著性差异( P>0 .05)。结论 肝前型门脉高压症的术式选择应根据术前全身状况、门脉压力增高程度并结合各种术式降压效果而定,并提出术式选择的三项标准
Objective To provide the basis for surgical selection of prehypertensive portal hypertension. Methods The method of narrowing the portal vein was used to make animal model of hepatic portal hypertension. 18 cases of hepatic prehypertensive disease were divided into 4 groups, which were divided into splenectomy, splenectomy, periocardial vascular disconnection, intestine shunt and combined surgery respectively. Portal pressure was measured before and after surgery for comparison. Results Compared with preoperative, splenectomy could reduce the portal pressure (P <0.05). The optimal effect was relieved by shunt of intestine (P <0.001). There was no significant difference between splenectomy and resection (P <0.01). However, there was no significant difference in the hypotensive effect between the shunt and the combined surgery (P> 0.05). Conclusion The choice of surgical procedure should be based on the preoperative status of the whole body, the increase of portal pressure combined with the effect of various surgical decompression, and propose three criteria