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目的:探讨支气管内微波治疗联合局部瘤体注射治疗中央型肺癌的疗效。方法:将2006-02/2009-05齐齐哈尔医学院附属第三医院呼吸内科收治的38例晚期中央型肺癌患者随机分为治疗组和对照组。治疗组20例采用支气管内微波治疗并局部瘤体注药,对照组18例仅进行局部瘤体注药。结果:20例治疗组平均微波治疗联合药物注射3.5次,症状改善率90%,KPS评分提高率95%,支气管镜下病灶好转率80%,胸部CT肺不张或阻塞性肺炎好转率75%,与对照组相比差异有统计学意义(P<0.05)。结论:晚期中央型肺癌患者采用支气管内微波治疗联合局部瘤体注射疗法,能有效的缓解呼吸困难,解除阻塞,提高生活质量,且优于单纯局部药物注射疗法。
Objective: To investigate the therapeutic effect of intrabronchial microwave combined with local tumor injection in the treatment of central lung cancer. Methods: Thirty-eight patients with advanced central lung cancer who were admitted to Department of Respiratory Medicine, the Third Affiliated Hospital of Qiqihar Medical College from February 2006 to May 2009 were randomly divided into treatment group and control group. Twenty patients in the treatment group were treated with intrabronchial microwave and the local tumor was injected. In the control group, only 18 cases were injected with local tumor. Results: In the 20 treatment groups, the average microwave treatment combined with drug injection 3.5 times, 90% improvement in symptoms, 95% improvement in KPS score, 80% improvement in bronchoscopy lesions, chest CT atelectasis or obstructive pneumonia improvement rate of 75% , Compared with the control group, the difference was statistically significant (P <0.05). Conclusion: The treatment of patients with advanced central lung cancer by intrabronchial microwave combined with local tumor injection therapy can effectively relieve dyspnea, relieve obstruction and improve the quality of life, and is better than simple local injection therapy.