Triterpene saponins with XOD inhibitory activity from the roots of Ilex pubescens

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:zhanghongyingyxl
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A new triterpene saponin with 28-nor-urs-12(13),18(17)-dien-3β-ol as aglycone,named ilexsaponin C(1) was isolated from the roots of Ilex pubescens,together with three known saponins 2,3 and 4.The structure of 1 was elucidated on the basis of spectral analysis including 1D and 2D NMR and HR-ESI-MS.Saponins 1 and 4 exhibited significant XOD inhibitory activity in the test. A new triterpene saponin with 28-nor-urs-12 (13), 18 (17) -dien-3β-ol as aglycone, named ilexsaponin C (1) was isolated from the roots of Ilex pubescens, together with three known saponins 2 , 3 and 4. The structure of 1 was elucidated on the basis of spectral analysis including 1D and 2D NMR and HR-ESI-MS.Saponins 1 and 4 exhibits significant XOD inhibitory activity in the test.
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