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E钙粘蛋白是上皮型钙依赖性细胞粘附分子,它调节细胞-细胞之间的相互关系,在正常的细胞生长、增殖中起重要的作用。近来研究表明,E钙粘蛋白在抑制肿瘤的浸润转移方面也有一定的作用。本实验采用免疫组化染色和计算机图像分析对肾癌细胞中的E钙粘蛋白表达与肾癌发生、浸润和
E-cadherin is an epithelial calcium-dependent cell adhesion molecule that regulates cell-cell interactions and plays an important role in normal cell growth and proliferation. Recent studies have shown that E-cadherin also plays a role in inhibiting tumor invasion and metastasis. In this study, immunohistochemical staining and computer image analysis of renal cell carcinoma E-cadherin expression and renal cell carcinoma, infiltration and