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[目的]探讨可吸收人工骨粉修复跟骨粉碎性骨折的临床效果及生物相容性.[方法]纳入27例跟骨粉碎性骨折患者,均实施外侧“L”形入路骨折复位,复位后予以Genex人工骨粉进行骨缺损修复联合锁定钢板置入内固定治疗.观察手术相关情况,对患者进行Maryland足部功能评分,并测量B(o)hler角、Gissane角.[结果]27例患者均顺利完成手术治疗,手术时间55～90 min,平均70 min.术后所有患者切口均一期愈合,未出现切口感染或者皮瓣坏死等并发症.3例患者出现轻度切口皮缘坏死,均经积极对症处理后痊愈.全部病例随访10～18个月,平均12个月.末次随访时患者均达到骨性愈合.人工骨粉在术后6个月左右发生降解,12年个月后全部被吸收.术后12个月对患者进行Maryland足部功能评分,经评分和比较可以发现,较之术前,患者疼痛和功能以及对线、总分均显著提高.术后12个月,较之术前,患者的B(o)hler角显著增大,Gissane角显著缩小,较治疗前均得到显著的改善(P＜0.05).患者均未出现炎性或排异反应.[结论]利用可吸收人工骨粉对跟骨粉碎性骨折患者进行治疗可以获得理想的修复效果,促进骨折愈合,有效改善关节功能,并具有良好的生物相容性.“,”[Objective] To investigate clinical outcome and compatibility of bioabsorbable artificial bone for repair comminuted fracture of calcaneus.[Methods] Twenty-seven patients with comminuted calcaneal fracture were surgically treated by open reduction,GeneX artificial bone implantation to fill the bone defects combined with locking plate internal fixation through the “L” lateral shaped approach.Maryland foot score,B(o)hler angle and Gissane angle measured on the X-ray films were used for evaluation of the consequence.[Results] All the patients were successfully completed surgery,with operation time of 70 min on average ranged from 55 to 90min.The incision healed in all patients,without complications such as wound infection or flap necrosis.However,3 patients had mild skin necrosis on incision edges,which healed following a proper active treatment.All the patients were followed up for an average of 12 months ranged from 10 to 18 months.At the latest follow-up,all of them achieved bony healing.The implanted artificial bone was degraded at 6 months,and absorbed completely atl2 months after operation.Maryland foot scores,including pain,function,alignment and total score,significantly increased at 12 months after operation compared with those before operation (P＜0.05).In addition,B(o)hler angle significantly increased whereas Gissane angle significantly reduced at the latest follow up,compared with those before surgery (P＜0.05).No inflammatory reaction or rejection happened in any patient.[Conclusion] Application of this absorbable artificial bone for comminuted calcaneus fracture achieves satisfactory results in maintaining reduction and improving fracture healing with a good biocompatibility.