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[目的]观察润肺止咳汤治疗小儿咳嗽变异性哮喘疗效。[方法]使用随机平行对照方法,将124例门诊及住院患者按就诊顺序编号法分为两组。对照组62例氨茶碱,每次3~5mg/kg,4次/d,口服。青霉素200~800万U+250mL5%葡萄糖,1次/d,静滴。治疗组62例润肺止咳汤(桔梗、前胡、法半夏、陈皮、紫菀炙、款冬花炙、川贝母、远志炙、杏仁、蜂蜜各6g,甘草炙3g,广州三九药业公司免煎颗粒剂),1剂/d,水冲早晚口服;痰多加茯苓、泽泻、胆星各6g;气喘加炙麻黄、苏子、地龙各6g,生龙骨、生牡蛎各15g;鼻塞、流清涕及打喷嚏加苍耳子、辛夷、薄荷、白芷各6g;自汗加防风、白术各6g,黄芪15g。连续治疗3d为1疗程。观测临床症状、临床症状改善情况、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效44例,有效16例,无效2例,总有效率96.78%,对照组显效25例,有效24例,无效13例,总有效率79.03%。治疗组疗效优于对照组(P<0.05)。临床症状改善情况两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]润肺止咳汤治疗小儿咳嗽变异性哮喘效果显著,值得推广。
[Objective] To observe the curative effect of Runfei Zhike Decoction on children with cough variant asthma. [Methods] Using randomized parallel control method, 124 outpatients and inpatients were divided into two groups according to the sequence number of visiting doctor. Control group, 62 cases of aminophylline, each 3 ~ 5mg / kg, 4 times / d, orally. Penicillin 200 ~ 8000000 U + 250mL5% glucose, 1 / d, intravenous infusion. In the treatment group, 62 cases of Runfeizhike Decoction (Campanulaceae, Peucedanum, Pinellia, Citrus, Aster, Asparagus, Fritillaria, Polygalaceae, Almonds, Honey 6g, licorice Sunburn 3g, Guangzhou 39 Pharmaceutical Company Free ointment granules), 1 / d, water wash sooner or later oral; sputum plus Poria, Alisma, gall G 6g; asthma plus burdock, Su son, earthworm each 6g, raw keel, raw oyster each 15g; , Runny nose and sneezing plus cocklebur, Magnolia, mint, Angelica 6g; spontaneous plus wind, Atractylodes each 6g, Astragalus 15g. Continuous treatment of 3d for a course of treatment. Observation of clinical symptoms, clinical symptoms, adverse reactions. Continuous treatment of 3 courses to determine the efficacy. [Result] In the treatment group, 44 cases were markedly effective, 16 cases were effective, 2 cases were ineffective, and the total effective rate was 96.78%. In the control group, 25 cases were markedly effective, 24 cases were effective and 13 cases were ineffective. The total effective rate was 79.03%. The treatment group was better than the control group (P <0.05). The improvement of clinical symptoms were improved in both groups (P <0.05), and the treatment group improved better than the control group (P <0.05). [Conclusion] Runfei Zhike Decoction has a significant effect in treating cough variant asthma in children and is worth promoting.