论文部分内容阅读
目的 :提高对非清除性异基因外周血干细胞移植 ( NAPBSCT)及移植后发生重度移植物抗宿主病( GVHD)的认识。方法 :报告该院 2例恶性血液病非清除性异基因外周血干细胞移植后发生重度 GVHD并文献复习。结果 :1例于移植后 6 2天痊愈 ,已健康生存 2 0月 ,另 1例移植后 5 1天死亡。结论 :NAPBSCT为恶性血液病的治疗开辟了新思路。 NAPBCT后可能会发生严重的 GVHD,应引起注意
Objective :To improve the understanding of non-scavenging allogeneic peripheral blood stem cell transplantation (NAPBSCT) and the occurrence of severe graft-versus-host disease (GVHD) after transplantation. METHODS: Two cases of hematologic malignancies with non-debralized allogeneic peripheral blood stem cells were reported to have severe GVHD and reviewed in the literature. Results : One patient recovered after being implanted on day 62 after transplantation. He had survived healthy living for 20 months and another patient died 51 days after transplantation. Conclusion : NAPBSCT opens up new ideas for the treatment of hematological malignancies. Severe GVHD may occur after NAPBCT and should attract attention