患者男，67岁。入院前30年始，每隔7～10天即出现不明原因发热，体温变化在37.5℃～39℃之间，同时伴有外周血白细胞总数减少，大多在（1～3）×109／L，反复行骨髓检查20多次，结果为粒系增生低下，其他各系细胞无成熟障碍，后脾至肋下3cm，质中，未见其它浅表淋巴结肿大。于1 Male patient, 67 years old. 30 years before admission, every 7 to 10 days, unexplained fever occurs, body temperature changes between 37.5°C and 39°C, and the total number of white blood cells in peripheral blood decreases, mostly at (1 to 3) × 109/L. The bone marrow examination was performed more than 20 times. The result was that the granulocytic growth was low, and there was no mature disorder in the cells of the other lines. The spleen was 3 cm below the ribs. No other superficial lymph nodes were enlarged. Yu 1