论文部分内容阅读
免疫机理在心脏病中的作用,如同它在身体其它各器官中的作用一样。自从首次提出许多慢性炎症疾患,实质是自发的和自身破坏性的自身免疫病以来,人们对这些免疫反应的病理作用的理解已发生变化。在某些慢性病,但并非所有慢性病,发现了同机体自身组织反应的自身抗体。自身抗体对于像甲状腺或心脏这样的组织来说,可以是特异的,或者可以非特异地同多种细胞核、线粒体及细胞产物反应。甚至当一种自身免疫反应很明显时,有时表示感染的间接结果以及对
The immune mechanism acts in heart disease just as it does in other organs of the body. The understanding of the pathological role of these immune responses has changed since the first time that many chronic inflammatory disorders were proposed, essentially spontaneous and self-destructive autoimmune diseases. In some chronic diseases, but not all chronic diseases, autoantibodies that react with the body’s own tissues are found. Autoantibodies can be specific to tissues like the thyroid or heart, or they can react non-specifically with a variety of nuclei, mitochondria and cellular products. Even when an autoimmune response is obvious, it sometimes indicates the indirect result of the infection and