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目的 探讨睾丸切除对人唾液表皮生长因子（ＥＧＦ） 分泌的影响。方法：应用放射免疫测定（ＲＩＡ） 方法对１１例因前列腺癌切除睾丸和２２ 例正常人唾液ＥＧＦ 含量进行了检测。结果：人睾丸切除后人唾液ＥＧＦ 含量１３－３２ ±４ ．３３（ｎｇ／１５ ｍｉｎ） ，与术前１４－０７ ±４ ．５０（ｎｇ／１５ ｍｉｎ） 比较，ｔ＝ １ ．７２５２ ，０ ．２ ＞ Ｐ＞ ０ ．１ ；与正常男性唾液ＥＧＦ 含量１３－９１ ±３ ．９０（ｎｇ／１５ｍｉｎ） 比较，ｔ ＝ ０ ．３９４６ ，Ｐ＞ ０ ．２５ ；均无显著性差别。结论：睾丸缺失对ＥＧＦ 影响不明显
Objective To investigate the effect of orchiectomy on the secretion of human saliva epidermal growth factor (EGF). Methods: Radioimmunoassay (RIA) was used to detect the EGF content in 11 cases of testis resected by prostate cancer and 22 cases of normal human saliva. Results: Human saliva after orchiectomy EGF content of 13-32 ± 4. 33 (ng / 15 min) compared with 14-07 ± 4 before surgery. 50 (ng / 15 min), t = 1. 7252, 0. 2> P> 0. 1; with normal male saliva EGF content 13-91 ± 3. 90 (ng / 15min), t = 0. 3946, P> 0. 25; no significant difference. Conclusion: Testicular loss has no obvious effect on EGF