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本文测定了53例慢性肺心病患者和36例健康人的血浆心钠素的含量。结果:肺心病组急性发作期和缓解期的血浆心钠素分别为3628±645 Pg/ml和2692±759Pg/ml均显著高于健康人的血浆浓度326±31Pg/ml(P<0.001)。肺心病急性发作期高于缓解期,但两者之间无统计学差异。提示肺心病患者心钠素含量增高可能主要是患者右心房充盈压高以及对机体存在水钠潴留倾向的代偿反应。简要探讨了心钠素与有关影响水钠潴留因素的关系。
In this paper, we measured the plasma atrial natriuretic peptide levels in 53 patients with chronic cor pulmonale and 36 healthy subjects. Results: Plasma atrial natriuretic peptide levels of 3628 ± 645 Pg / ml and 2692 ± 759 Pg / ml in patients with pulmonary heart disease during acute exacerbation and remission were significantly higher than those in healthy subjects (P <0.001). Pulmonary heart disease acute exacerbation period higher than the remission, but no significant difference between the two. Tip of patients with pulmonary heart disease increased atrial natriuretic peptide may be mainly due to patients with right atrial filling pressure and the existence of the body Shuinazhuliu tendency compensatory response. A brief discussion of the relationship between atrial natriuretic factor and water and sodium retention factors.