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目的探讨多巴胺联合磷酸肌酸钠治疗新生儿缺氧性心肌损害的临床疗效。方法将62例确诊为心肌损害的新生儿随机分为观察组(31例)和对照组(31例),对照组患儿在常规对症支持治疗的基础上加用磷酸肌酸钠,观察组患儿在常规对症支持治疗的基础上加用多巴胺联合磷酸肌酸钠,观察两组患儿心音、心电图、心率、心肌酶等在治疗前后的变化。结果两组患儿经治疗后心肌酶谱各项指标均下降,但观察组患儿下降程度大于对照组患儿(P<0.05),观察组患儿的治疗总有效率高于对照组患儿(P<0.05)。结论采用多巴胺联合磷酸肌酸钠治疗新生儿缺氧新心肌损害疗效确切,值得临床推广
Objective To investigate the clinical efficacy of dopamine and sodium creatine phosphate in neonatal hypoxic myocardial damage. Methods Totally 62 neonates diagnosed as myocardial damage were randomly divided into observation group (31 cases) and control group (31 cases). Patients in control group were given sodium creatine phosphate on the basis of conventional symptomatic supportive therapy. Children in the conventional symptomatic and supportive treatment based on the addition of dopamine combined with creatine sodium phosphate, observed in two groups of children with heart sound, electrocardiogram, heart rate, myocardial enzyme changes before and after treatment. Results After treatment, the indexes of myocardial enzymes decreased in both groups, but the degree of decrease in the observation group was more than that in the control group (P <0.05). The total effective rate in the observation group was higher than that in the control group (P <0.05). Conclusion Dopamine combined with creatine phosphate in the treatment of neonatal hypoxic myocardial damage is effective and worthy of clinical promotion