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  5. An efficient chiral synthesis of (R)-N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl]-butan

An efficient chiral synthesis of (R)-N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl]-butan

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：dongshengly
【摘 要】
：
R-Enantiomer of the β-receptor antagonist N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl] butanamide with high enantioselectivity was synthesized fro
【作 者】
：
NaiXing Wang (1) (2)  XinLia 
【机 构】
：
1.TechnicalInstituteofPhysicsandChemistry,2.CollegeofChemistryandChemicalEngineering,3.SchoolofChemi
【出 处】
：
中国科学：化学英文版
【发表日期】
：
2009年8期
【关键词】
：
CHIRAL synthesis ENANTIOSELECTIVITY enatiomeric excess CHIRAL HPLC analysis chir 
【基金项目】
：
Supported by the National Natural Science Foundation of China (Grant Nos. 20472090 & 10576034),PLA General Armament Department (Grant No. 9140A28010707zk7301)
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R-Enantiomer of the β-receptor antagonist N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl] butanamide with high enantioselectivity was synthesized from cheap starting materials and enantiopure chiral reagent through an efficient,convenient and pr
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