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作者使用三个厂制备的8批A群流脑多糖菌苗,各皮下注射0.5ml内含10或50μg抗原,以观察婴儿及儿童(年龄从两个月到4.4岁)的应答,接种前和接种后28或35天采静脉血,用放射性抗原结合试验以测定抗体,并以每毫升少于0.19μg为不能测出的限度。
The authors used eight batches of Group A meningitidis prepared in three plants, each subcutaneously injected with 0.5 ml containing 10 or 50 μg of antigen to observe the response of infants and children (two months to 4.4 years of age) Venous blood was collected 28 days or 35 days after inoculation and antibodies were determined using a radioactive antigen binding assay with an unmeasurable limit of less than 0.19 μg / ml.