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目的通过病例报道及文献复习探讨肺良性转移性平滑肌瘤的临床特点,提高临床医师对该病的认识。方法对收治的4例肺良性转移性平滑肌瘤患者的临床资料进行回顾性分析及相关文献复习。结果 4例患者均有子宫平滑肌瘤病史,且均行手术治疗,CT示4例患者均有肺内多发性结节,其中1例患者伴有腹膜多发转移。3例患者行CT引导下穿刺,1例行胸腔镜下楔形切除部分肺组织。病理提示平滑肌源性肿瘤。结论肺良性转移性平滑肌瘤临床少见,多发生在有子宫平滑肌瘤病史的女性,可通过CT引导下穿刺、胸腔镜活检确诊,手术切除及抗雌激素治疗为主要治疗方法。
Objective To investigate the clinical features of benign pulmonary metastatic leiomyoma by case reports and literature review, and to improve clinicians’ understanding of the disease. Methods The clinical data of 4 patients with benign pulmonary metastatic leiomyoma treated by retrospective analysis and literature review. Results All the 4 patients had a history of uterine leiomyoma, and all underwent surgical treatment. CT showed that all 4 patients had multiple intrapulmonary nodules, of which 1 patient had multiple peritoneal metastasis. Three patients underwent CT-guided puncture and one underwent thoracoscopic wedge resection of part of the lung tissue. Pathology prompted smooth muscle-derived tumors. Conclusions The lung benign metastatic leiomyoma is rare in clinic and occurs mostly in women with a history of uterine leiomyoma. CT - guided puncture, thoracoscope biopsy, surgical resection and anti - estrogen therapy are the main treatment methods.