血管性假血友病(vonWillebrand Disease,vWD的基本缺陷是由于血管性假血友病因子(von Willebrand factor,vWF)量及/或质饮异常所致。目前,常用瑞斯托霉素(Ristocetin)诱导血小板聚集试验(Ristocetin induced platelat agg-regation,RIPA)作为诊断vWD的定性初筛试验,但有部分患者呈阴性结果,显示RIPA不甚敏感。本文利用瑞斯托霉素辅因子定量试验(vWF-Ri- Von Willebrand Disease (vWD) is caused by an abnormal amount of von Willebrand factor (vWF) and / or an abnormal quality of drinking water. Currently, Ristocetin (RIPA) was used as a qualitative screening test for the diagnosis of vWD, but some patients showed negative results, indicating that RIPA was not sensitive.In this paper, Ristocetin Cofactor Quantitative Assay vWF-Ri-