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目的:分析脑梗塞认知功能与颈动脉斑块、CRP、Hcy及脑白质病变等相关性.方法:将60例脑梗塞认知损害患者作为试验组和同期住院无认知损害患者62例作为对照组.两组分别检测颈动脉彩超、血清C R P及Hcy水平、WML情况.结果:两组患者血清CRP及Hcy水平均有升高,试验组升高更为明显(P<0.05).但是试验组颈动脉斑块异常水平比对照组更为显著(P<0.05).结论:颈动脉不稳定斑块、CRP、Hcy及WML是急性脑梗塞发生认知功能损害的重要危险因素.“,”Objective To analyse relationship of cognition with carotid plaque, CRP, Hcy and cerebral white lesions. Methods 60 cases cognitive impairment patients were experiment group, and 62 cases with no cognitive impairment were control. Compare the the level of CRP and Hcy, carotid plaque and WML.Results Serum CRP and Hcy levels of all patients increased, experiment group was higher than control (P<0.05). The carotid plaque of experiment group was more abnormal than control (P<0.05).Conclusions The unstable carotid plaque,serum CRP Hcy and WML were risk factor of cerebral infraction.