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目的探讨脉络宁对糖尿病 (DM)周围血管神经病变及甲襞微循环的影响和作用。方法74例DM病人随机分为两组 ,治疗组39例 ,对照组35例 ,分别观察两组间治疗前后的临床症状、体征变化及甲装微循环的改变。结果1、治疗前后疗效两组间对比有显著性差异 ,P<0.05;2、脉络宁治疗组甲襞微循环改变 ,治疗前后差异显著 ,P<0.01,对照组治疗前后无明显变化 ,P>0.05;3、两组间治疗前后甲襞微循环加权积分值差异显著 ,P<0.05。结论脉络宁对DM周围神经病变及微循环有明显改善作用 ,与对照组相比 ,具有见效快、疗效好、安全、可靠之优点
Objective To investigate the effect and mechanism of Mailuoning on peripheral neuropathy and microcirculation in diabetic rats (DM). Methods A total of 74 patients with DM were randomly divided into two groups: the treatment group (39 cases) and the control group (35 cases). The clinical symptoms, signs and changes of microcirculation were observed before and after treatment. There was significant difference between the two groups before and after treatment (P <0.05); 2, Mailuoning treatment group changes of microcirculation, before and after treatment significant difference, P <0.01, the control group before and after treatment no significant change, P> 0.05; 3, There was significant difference between the two groups before and after treatment of microcirculation weighted integral value, P <0.05. Conclusion Mailuoning on DM peripheral neuropathy and microcirculation were significantly improved compared with the control group, with quick, good effect, safe, reliable advantages