目的观察血清尿酸(SUA)、高敏C-反应蛋白(hs-CRP)浓度在急性ST段抬高型心肌梗死(STEMI)中的变化。方法选取2011年3月-2013年8月该院收治的STEMI患者50例作为观察组,50例门诊健康体检者作为对照组,采用尿酸酶法及免疫散射光比浊法分别测定2组患者的血清SUA及hs-CRP浓度。结果观察组患者血清SUA、hs-CRP水平均高于对照组,差异均有统计学意义(P<0.01)。结论高血清SUA、hs-CRP水平可能是导致STEMI的危险因素,可能与STEMI的发生有关。 Objective To investigate the changes of serum uric acid (SUA) and high sensitivity C-reactive protein (hs-CRP) in acute ST-segment elevation myocardial infarction (STEMI). Methods From March 2011 to August 2013, 50 patients with STEMI admitted to the hospital were selected as the observation group and 50 healthy subjects were selected as the control group. Uricase and immunostaining nephelometry were used to determine the levels of Serum SUA and hs-CRP concentrations. Results The serum levels of SUA and hs-CRP in the observation group were significantly higher than those in the control group (P <0.01). Conclusion High serum levels of SUA and hs-CRP may be the risk factors for STEMI, which may be related to the occurrence of STEMI.