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目的:探究重度低钾血症患者采取高浓度快速补钾的临床疗效及安全性,为最优化补钾方案积累经验。方法:选取我院急诊科于2011年3月~2013年3月收治的100例重度低钾血症患者,利用随机数字表法进行分组,分别设为研究组和对照组,每组各50例。对照组采取慢速补钾,研究组采取快速补钾。结果:①两组患者的钾注射量、治疗前血钾浓度差异不存在统计学意义(P>0.05);研究组钾注射时间短于对照组(P<0.05),治疗后血钾浓度高于对照组(P<0.05)。②研究组不良症状发生率低于对照组(P>0.05)。结论:高浓度快速补钾治疗相较于慢速补钾而言,不仅能快速提高血钾水平,且安全性高,值得进一步推广。
Objective: To explore the clinical efficacy and safety of high potassium concentration in patients with severe hypokalemia and to gain experience for the optimal potassium regimen. Methods: One hundred patients with severe hypokalemia admitted to our emergency department from March 2011 to March 2013 were selected and randomly divided into study group and control group, with 50 cases in each group . The control group take slow potassium, the research group to take fast potassium. Results: ① There was no significant difference between the two groups in the amount of potassium injection and the serum potassium concentration before treatment (P> 0.05). The potassium injection time in the study group was shorter than that in the control group (P <0.05) Control group (P <0.05). ② The incidence of adverse symptoms in the study group was lower than that in the control group (P> 0.05). Conclusion: Compared with the slow potassium supplement, high-concentration rapid potassium supplement can not only rapidly increase serum potassium levels, but also be safe and worth further promotion.