作者利用能使心血管药物选择性地产生具电活性光降解品的光化学反应器(PCR)与HPLC系统联用(安装在其柱与检测器间)组成的HPLC-光解-电化学检测系统,进行含安体舒通单一成分片或同时含有氢氯噻嗪双成分片的含量测定。为获取最大电位反应,还完成了流动相pH值和PCR紫外线照射时间最优化选择实验。实验结果表明,5μm氰基键合相柱和甲醇-磷酸盐缓冲液的流动相9分钟内即可将安体舒通、氢氯噻嗪、-4氨-6-氯-1,3-苯二磺胺(氢氯噻嗪的合成前 The authors used an HPLC-photolysis-electrochemical detection system consisting of a photochemical reactor (PCR) that enables cardiovascular drugs to selectively produce electro-active photodegradation products in conjunction with an HPLC system (mounted between their column and detector) , Containing spironolactone single component tablets or both contain hydrochlorothiazide content of two-component tablets. In order to obtain the maximum potential reaction, the optimization of the mobile phase pH and PCR UV irradiation time was also completed. The experimental results show that spironolactone, hydrochlorothiazide, 4-amino-6-chloro-1,3-benzene disulfonamide Hydrochlorothiazide before synthesis