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目的探讨阿托伐他汀治疗颈动脉粥样硬化的临床疗效。方法将我院颈动脉粥样硬化患者120例随机分为两组各60例,对照组根据原发疾病给予相应治疗,观察组在此基础上给予阿托伐他汀治疗,观察两组疗效。结果观察组治疗后TC、TG、LDL水平下降程度和HDL升高程度均较对照组明显,差异有统计学意义(P<0.05)。观察组治疗后斑块面积和IMT值改善程度优于对照组,差异有统计学意义(P<0.05)。结论阿托伐他汀治疗颈动脉粥样硬化可以有效缩小颈动脉粥样硬化斑块,改善患者血脂状况,值得临床推广。
Objective To investigate the clinical efficacy of atorvastatin in the treatment of carotid atherosclerosis. Methods A total of 120 patients with carotid atherosclerosis in our hospital were randomly divided into two groups of 60 patients. The control group was given corresponding treatment according to the primary disease. The observation group was given atorvastatin on this basis, and the curative effect was observed. Results The decrease of TC, TG and LDL and the increase of HDL in observation group after treatment were significantly higher than those in control group (P <0.05). The improvement of plaque area and IMT after treatment in observation group was better than that in control group, the difference was statistically significant (P <0.05). Conclusion Atorvastatin treatment of carotid atherosclerosis can effectively reduce carotid atherosclerosis plaque, improve blood lipid status in patients, it is worth clinical promotion.