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目的观察替罗非班在急性ST段抬高型心肌梗死(STEMI)介入治疗中的有效性及安全性。方法选取医院心内科收治的急性STEMI患者42例,随机分为对照组和观察组,每组21例。对照组实施常规治疗,观察组在对照组治疗基础上联合应用替罗非班治疗,观察2组用药效果、TIMI血流分级状况、MBG分级情况、出血情况等,以评价该方案安全性及有效性。结果患者实施2种方案后,观察组TIMI血流分级、MBG分级均优于对照组(P<0.05)。观察组无出血患者,出现患者死亡1例(4.76%);对照组中有出血1例(4.76%),死亡2例(9.52%),2组比较差异无统计学意义(P>0.05)。结论对于出现急性STEMI患者,急诊介入治疗时,通过实施替罗非班治疗方案,在提高患者介入治疗效果的基础上,使其TIMI血流分级、MBG分级状况均有效改善,从而提高预后效果,具有良好的安全性及有效性。
Objective To observe the efficacy and safety of tirofiban in the interventional treatment of acute ST-segment elevation myocardial infarction (STEMI). Methods Forty-two acute STEMI patients admitted to the hospital were randomly divided into control group and observation group, 21 cases in each group. The control group was given routine treatment. The observation group was treated with tirofiban on the basis of the control group. The effects of the two groups were observed, TIMI grade, MBG grade, bleeding, etc. to evaluate the safety and effectiveness Sex. Results After the two kinds of regimens were implemented, TIMI grade and MBG grade in the observation group were better than those in the control group (P <0.05). One patient (4.76%) died in the observation group and one patient died in the control group (4.76%) and two died (9.52%). There was no significant difference between the two groups (P> 0.05). Conclusion In acute STEMI patients, through the implementation of tirofiban regimen, the interventional treatment of acute STEMI can improve the TIMI blood flow classification and MBG grading condition on the basis of improving the effect of interventional therapy in patients with acute STEMI, so as to improve the prognosis, Has good safety and effectiveness.