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我们对８７例经病理诊断为视网膜母细胞瘤（ＲＢ）并有视神经或脉络膜侵犯的病理切片作详细复查，分析其就诊年龄、病程、临床分期及组织学分型与视神经、脉络膜受累的关系。发现视神经、脉络膜受侵犯的程度随病程的延长而增加，肿瘤的扩散、转移与肿瘤细胞分化的程度亦有一定关系。提出临床应与病理紧密联系，根据病理检查结果作出相应的治疗选择，以减少ＲＢ转移的危险因素。同时，还就随访的２３例病人进行简要分析。
We performed a detailed review of 87 pathologically diagnosed retinoblastoma (RB) and optic nerve or choroidal invades, and analyzed the relationship between the age, course of disease, clinical stage, histological type and optic nerve and choroidal involvement. It was found that the degree of optic nerve and choroid invasion increased with the prolongation of the course of disease. The spread and metastasis of tumor also had a certain relationship with the degree of tumor cell differentiation. Put forward the clinical should be closely linked with the pathology, according to the results of pathological examination to make the appropriate treatment options to reduce the risk of RB metastasis. At the same time, a brief analysis of 23 patients followed up was also conducted.