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目的观察奥美拉唑联合复方尿囊素治疗胃溃疡合并出血患者的临床治疗效果。方法选取2015年6月-2017年2月收治的胃溃疡合并出血患者76例,随机分为观察组和对照组,每组38例。对照组患者在常规治疗的基础上给予奥美拉唑胶囊治疗;观察组患者在对照组治疗的基础上给予复方尿囊素治疗。比较2组疗效及不良反应。结果观察组总有效率为94.74%高于对照组的78.95%,差异有统计学意义(χ2=4.1454,P<0.05)。观察组不良反应发生率为15.79%(6/38),对照组不良反应发生率为10.53%(4/38),2组不良反应发生率比较差异无统计学意义(χ2=0.4606,P>0.05)。结论奥美拉唑联合复方尿囊素治疗胃溃疡合并出血临床治疗效果显著,且无明显不良反应发生,值得临床上进一步推广应用。
Objective To observe the clinical effect of omeprazole combined with compound allantoin in the treatment of patients with gastric ulcer combined with hemorrhage. Methods 76 patients with gastric ulcer combined with hemorrhage admitted from June 2015 to February 2017 were randomly divided into observation group and control group with 38 cases in each group. Patients in the control group were treated with omeprazole capsules on the basis of routine treatment. Patients in the observation group were given compound allantoin on the basis of the control group. The curative effect and side effects of two groups were compared. Results The total effective rate in observation group was 94.74%, which was significantly higher than 78.95% in control group (χ2 = 4.1454, P <0.05). The incidence of adverse reactions in the observation group was 15.79% (6/38), and the incidence of adverse reactions in the control group was 10.53% (4/38). There was no significant difference in the incidence of adverse reactions between the two groups (χ2 = 0.4606, P> 0.05 ). Conclusion Omeprazole combined with compound allantoin in the treatment of gastric ulcer combined with bleeding clinical significant effect, and no significant adverse reactions, it is worth further clinical application.