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目的：研究中药降粘抗栓片Ｉ号对犬急性心肌缺血状态下的血液流变学改变．方法：用犬作为实验对象，结扎其冠状动脉，造成心肌急性缺血，经胃一次性灌入两种不同浓度的降粘抗栓片Ｉ号混悬液，从心大静脉留取不同实验时间点的血样，测定和计算全血高切、低切粘度、血浆粘度、红细胞比容等１０项血液流变学指标．结果：该中药制剂能降低全血高切、低切粘度、血浆粘度和加快红细胞电泳时间及电泳率，对红细胞比容无明显影响．结论：降粘抗栓片Ｉ号能改善犬急性心肌缺血状态下的血液流变行为，可用于血液高粘滞综合征的预防和治疗．
3. Objective : To study the hemorheological changes of Chinese medicine Jiangzhi Jiangan Antithrombotic Tablet I on dogs with acute myocardial ischemia. METHODS: Dogs were used as experimental subjects, and their coronary arteries were ligated to cause acute myocardial ischemia. Two different concentrations of Jiangmin Kangshuan Tablet No. I suspension were injected into the stomach at one time. Different experimental time was taken from the great cardiac veins. Blood samples at the point, determination and calculation of whole blood high-cut, low-cut viscosity, plasma viscosity, hematocrit and other 10 hemorheological parameters. RESULTS: The traditional Chinese medicine preparation can reduce high-cut, low-cut viscosity, plasma viscosity, and increase the electrophoresis time and electrophoretic rate of red blood cells, and has no significant effect on the hematocrit. Conclusion: Jiangzhi Kangshuan Tablet I can improve the rheological behavior of dogs with acute myocardial ischemia. It can be used for the prevention and treatment of hyperviscosity syndrome in blood.