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目的:对结肠、直肠癌活检病理诊断情况进行探讨分析,为临床诊断提供参考。方法:对206例结肠、直肠癌患者活检病理标本的石蜡切片进行阅片,观察癌侵和黏膜下层的浸润情况,与相应术后病理诊断进行比较,对活检病理诊断情况进行探讨。结果:206例结肠、直肠癌患者活检病理标本的石蜡切片和术后病理诊断进行比较,有189例(91.75%)诊断为结肠、直肠癌,17例(8.25%)诊断为腺瘤癌变。123例(59.71%)患者癌侵和黏膜下层的浸润情况无法判断,术后病理诊断为侵润癌。结论:结直肠癌是常见的恶性肿瘤,病理活检是术前诊断的重要方法,但病理活检于多数结直肠癌无法判断癌侵和黏膜下层的浸润情况,不能据此简单诊断为上皮内瘤变。
Objective: To investigate the pathological diagnosis of colorectal cancer and biopsy, and to provide a reference for clinical diagnosis. Methods: Paraffin sections from biopsy specimens of 206 patients with colon and rectal cancer were read, and the invasiveness and submucosal invasion were observed. The pathological diagnosis was compared with the postoperative pathological diagnosis. Results: There were 189 cases (91.75%) diagnosed as colorectal cancer and 17 cases (8.25%) diagnosed as adenocarcinoma by paraffin section of biopsy specimens of 206 cases of colon and rectal cancer. 123 cases (59.71%) of patients with cancer invasion and submucosal infiltration can not determine the pathological diagnosis of invasive cancer. Conclusion: Colorectal cancer is a common malignant tumor. Pathological biopsy is an important method of preoperative diagnosis. However, pathological biopsy in most colorectal cancers can not determine the invasion of cancer and submucosal invasion, and can not be simply diagnosed as intraepithelial neoplasia .