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目的探讨C_3F_8或硅油填充对增生性糖尿病视网膜病变(PDR)玻璃体切割手术后玻璃体再积血及视力的影响。方法选择50例(62只眼)作为研究对象,根据玻璃体腔填充物的不同将患者分为C_3F_8填充组和硅油填充组,分别为24例29只眼和26例33只眼。比较两组患者术后玻璃体再积血的发生率、时间以及最佳矫正视力(BCVA)的变化情况。结果硅油填充组患者术后玻璃体再积血的发生率为12.12%,显著低于C_3F_8填充组的34.48%,且前者发生的时间为术后(169.31±15.78)d,其中在硅油取出1~3 d时出现的人数最多,占总发生人数的75.00%,显著长于后者的(64.11±15.72)d,在术后30~60 d出现的人最多,占总发生人数的87.50%;C_3F_8填充组患者BCVA为0.1以上的有19例,占比65.52%,显著高于硅油填充组患者的14例,39.39%(P<0.05)。结论硅油填充可有效降低术后玻璃体的再积血率,延缓积血的出现时间。
Objective To investigate the effects of C_3F_8 or silicone oil filling on vitreous hemorrhage and visual acuity after vitrectomy for proliferative diabetic retinopathy (PDR). Methods Fifty patients (62 eyes) were selected as study objects. According to the different filling of vitreous cavity, patients were divided into C_3F_8 filled group and silicone oil filled group, which were 29 eyes in 24 cases and 33 eyes in 26 eyes. The incidence of postoperative vitreous hemorrhage, the time and the best corrected visual acuity (BCVA) were compared between the two groups. Results The incidence of postoperative vitreous hemorrhage was 12.12% in the silicone oil-filled group, significantly lower than 34.48% in the C_3F_8-filled group, and the former time was 169.31 ± 15.78 days after the silicone oil was removed d, the number of occurrence was the largest, accounting for 75.00% of the total number of occurrence, significantly longer than the latter (64.11 ± 15.72) d, the largest number of people appeared 30 ~ 60 d postoperatively, accounting for 87.50% of the total; C_3F_8-filled group There were 19 patients with BCVA of 0.1 or more, accounting for 65.52%, significantly higher than those in silicone oil filled patients (14.39%, 39.39%, P <0.05). Conclusion Silicone oil filling can effectively reduce the post-vitreous hemorrhage rate and delay the appearance of hemorrhage.