乏氧是人和动物肿瘤共有的特征。实验观察与测定表明,几乎所有的实体肿瘤中均有乏氧细胞存在,乏氧细胞在实体瘤中是常见现象[1]。分子生物学研究发现[2,3],乏氧不仅使肿瘤产生针对放、化疗的保护蛋白,增加对放、化疗的抵抗性,而且使肿瘤内氧调节蛋白(OPR)、血管内皮生长因子(VE Hypoxia is a common feature of both human and animal tumors. Experimental observations and measurements show that almost all solid tumors exist hypoxic cells, hypoxic cells in solid tumors is a common phenomenon [1]. Molecular biology studies have found that hypoxia not only makes the tumor produce protection and protection against radiotherapy and chemotherapy, but also increases the resistance to radiotherapy and chemotherapy. In addition, the expression of tumor necrosis factor-alpha (OPR), vascular endothelial growth factor VE