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目的：评价乳腺浸润性导管癌生长方式的体视学参数及淋巴结转移情况与预后的关系。方法：根据体视学原理，采用模板法，测定癌实质体积密度（Vv）及癌巢的表面积密度（Sv）。观察H．E．切片进行淋巴结癌转移计数，比较Vv、Sv、淋巴结转移情况与预后的相关性。结果：在与预后有显著相关性的因素─淋巴结转移、癌实质体积密度（Vv）及癌巢的麦面积密度（Sv）中发现，Sv≤4．4的患者中，89．3％生存5年以上，Sv＞5．5的患者中，82．5％死于5年以内。结论：癌肿生长方式的体视学参数─Sv值可作为独立判断预后的因素，Vv、淋巴结转移是乳腺浸润性导管癌预后的相关因素。
Objective: To evaluate the relationship between stereological parameters and lymph node metastasis and prognosis in breast invasive ductal carcinoma. Methods: According to the principle of stereology, the Vv of cancer and the surface area density (Sv) of cancer nests were determined by the template method. Observe H. E. Slides were counted for lymph node metastasis, and the correlations between Vv, Sv, lymph node metastasis and prognosis were compared. RESULTS: Among the factors that were significantly associated with prognosis-lymph node metastasis, Vv and Sv, 89.3% of patients with Sv≤4.4 Years, Sv> 5.5 patients, 82.5% died within 5 years. CONCLUSIONS: Stereological parameters of cancer growth pattern, Sv value, can be used as an independent prognostic factor. Vv and lymph node metastasis are prognostic factors of breast invasive ductal carcinoma.