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目的:探讨妊娠期单纯葡萄糖筛查试验异常对妊娠的影响。方法:回顾性分析2007年1月～2010年6月在东莞市人民医院妇产科住院分娩的2 473例孕产妇资料,以其中葡萄糖筛查试验异常而口服葡萄糖耐量试验正常的628例为单纯葡萄糖筛查试验异常(GCT异常)组,以葡萄糖筛查试验正常的1 845例为GCT正常组,记录两组分娩时的孕周、破膜前B超检测的羊水指数、新生儿出生体重、身长及头围,比较两组羊水过多、早产、巨大儿、胎儿生长受限的发生率及新生儿出生体重、身长、头围。结果:GCT异常组胎儿生长受限发生率为2.5%,新生儿出生身长为(50.8±1.4)cm,头围为(34.2±1.5)cm;正常组胎儿生长受限发生率为2.9%,新生儿出生身长为(50.7±1.5)cm,头围为(34.1±1.4)cm,两组比较差异均无统计学意义(P>0.05)。GCT异常组羊水过多发生率为3.3%,早产发生率为5.3%,巨大儿发生率为11.5%,新生儿出生体重为(3.5±0.5)kg;GCT正常组羊水过多发生率为0.6%,早产发生率为2.5%,巨大儿发生率为4.7%,新生儿出生体重为(3.2±0.6)kg,两组指标比较差异均有统计学意义(P<0.05)。结论:单纯GCT异常的孕产妇羊水过多、早产、巨大儿的发生率及新生儿出生体重均高于GCT正常的孕妇。
Objective: To investigate the influence of abnormal glucose screening test during pregnancy on pregnancy. Methods: A retrospective analysis of 2 473 pregnant women with obstetrics and gynecology obstetrics and gynecology in Dongguan People’s Hospital from January 2007 to June 2010 was retrospectively analyzed. Among them, 628 cases with abnormal glucose screening test and normal oral glucose tolerance test Glucose screening test abnormalities (GCT abnormalities) group, the glucose screening test normal 1845 cases of GCT normal group, the gestational age at childbirth at the time of delivery, pre-rupture membrane B-amniotic fluid index, newborn birth weight, Length and head circumference, compared the incidence of polyhydramnios, prematurity, giant fetus, fetal growth restriction and newborn birth weight, length, head circumference. Results: The incidence of fetal growth restriction was 2.5% in the GCT abnormal group, (50.8 ± 1.4) cm in the newborn and (34.2 ± 1.5) cm in the head circumference. The normal fetal growth restriction was 2.9% The length of birth was (50.7 ± 1.5) cm and the head circumference was (34.1 ± 1.4) cm. There was no significant difference between the two groups (P> 0.05). The incidence of polyhydramnios in GCT abnormal group was 3.3%, the incidence of preterm birth was 5.3%, the incidence of macrosomia was 11.5%, the birth weight of neonates was (3.5 ± 0.5) kg; the incidence of polyhydramnios in GCT normal group was 0.6% , The incidence of preterm birth was 2.5%, the incidence of macrosomia was 4.7%, and the birth weight of newborns was (3.2 ± 0.6) kg. There was significant difference between the two groups (P <0.05). CONCLUSIONS: Excessive amniotic fluid levels in pregnant women with abnormal GCT, preterm birth, the incidence of macrosomia and newborn birth weight are higher than those with normal GCT.