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内折香茶菜乙素是从内折香茶菜 Rabdosia inf lexus(Thumb) Kundo叶中分离得出的一种新的二萜化合物 ,实验证明 ,在体外对艾氏腹水癌细胞有很强的细胞毒作用 ,对 L ewis肺癌 ,小鼠肉瘤 S1 80 实体型及腹水型、小鼠肝癌 HCA实体型及腹水型等均有明显的抗肿瘤作用 ,对以小鼠溶血素形成为指标的体液免疫有轻度抑制作用 ,而对由 DNCB诱导的小鼠迟发性超敏反应为指标的体内细胞免疫无明显影响
Intrinsine is a new diterpene compound isolated from the leaves of Rabdosia inf lexus (Thumb.) Kundo leaves. Experiments have shown that it is very strong against Ehrlich ascites carcinoma cells in vitro. Cytotoxicity has significant anti-tumor effect on Lewus lung cancer, mouse sarcoma S1 80 solid type and ascites type, mouse liver cancer HCA solid type and ascites type, and humoral immunity based on mouse hemolysin formation Mild inhibition, but no significant effect on in vivo cellular immunity as a marker of delayed-type hypersensitivity induced by DNCB in mice