论文部分内容阅读
目的观察小剂量β-受体阻滞剂治疗老年慢性充血性心衰患者的疗效。方法选择45例老年慢性充血性心衰患者,随机分成两组用不同方法治疗观察,观察组23例在常规应用强心、利尿、扩血管药物治疗的基础上加用小剂量β受体阻滞剂治疗,并与常规用药组22例对照;比较两组治疗前后患者临床症状、心功能、左室射血分数、心率和血压变化、药物副作用。结果观察组治疗后心率明显下降,LVEF明显上升,治疗的总有效率为91.3%(对照组为61.1%),与对照组比较均有非常显著差异(P<0.01);用药过程无严重副作用发生。结论在常规抗心衰药物治疗的基础上加用小剂量β受体阻滞剂可明显改善患者的心功能,提高临床疗效,改善生活质量,延长寿命。
Objective To observe the effect of low-dose β-blocker on elderly patients with chronic congestive heart failure. Methods Forty-five elderly patients with chronic congestive heart failure were randomly divided into two groups treated with different methods. In the observation group, 23 patients were treated with low dose β blockade on the basis of conventional cardiotomy, diuretic and vasodilator drug therapy And compared with the conventional treatment group (n = 22). The clinical symptoms, cardiac function, left ventricular ejection fraction, heart rate, blood pressure and drug side effects were compared between the two groups before and after treatment. Results After treatment, the heart rate decreased significantly and the LVEF increased obviously. The total effective rate was 91.3% (61.1% in the control group). There was a significant difference (P <0.01) between the control group and the control group. No serious side effects occurred during the treatment . Conclusion The addition of low-dose β-blockers to conventional anti-heart failure drugs can significantly improve cardiac function, improve clinical efficacy, improve quality of life, and prolong life expectancy.