【摘 要】
：
目的观察乙肝病毒携带者对丙泊酚用药量的影响。方法对37例乙肝病毒携带者和38例无肝胆疾病的静脉全麻手术患者,静脉推注芬太尼0.002mg/kg后继以4mg/(kg.min)的速度缓慢静脉
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目的观察乙肝病毒携带者对丙泊酚用药量的影响。方法对37例乙肝病毒携带者和38例无肝胆疾病的静脉全麻手术患者,静脉推注芬太尼0.002mg/kg后继以4mg/(kg.min)的速度缓慢静脉推注丙泊酚,直至睫毛反射消失。记录丙泊酚用量。结果丙泊酚用量乙肝病毒携带者组为(1.54±0.16)mg/kg,无肝胆疾病者组为(1.63±0.19)mg/kg,t=2.216,P<0.05,有统计学意义。结论乙肝病毒携带者丙泊酚诱导剂量减少。
Objective To observe the impact of hepatitis B virus carriers on propofol dosage. Methods Thirty-seven patients with hepatitis B virus infection and 38 patients without hepatobiliary disease underwent intravenous anesthesia. Propofol was slowly intravenously injected with 0.002 mg / kg fentanyl followed by 4 mg / (kg · min) Until the eyelash reflex disappears. Record the amount of propofol. Results The dosage of propofol was (1.54 ± 0.16) mg / kg in patients with hepatitis B virus carriers and (1.63 ± 0.19) mg / kg in patients without hepatobiliary diseases, t = 2.216, P <0.05. Conclusions Hepatitis B virus carrier propofol induced dose reduction.
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