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目的:观察彩超检测孕妇眼动脉血流参数与妊娠高血压疾病(HDCP)孕妇眼底病变的相关性,探讨其在临床HDCP诊断和治疗中的价值。方法:以40例正常孕妇作为对照组,测定73例HDCP组孕妇眼动脉搏动指数(PI)、阻力指数(RI)及收缩期第二峰(B)与第一峰(A)的比值(B/A);同时检查两组眼底改变,比较不同程度眼底病变时眼动脉血流参数的变化。结果:①眼动脉的PI、RI值与孕妇年龄及孕龄无明显相关(P>0.05),而B/A值与孕妇年龄有显著相关性(P<0.001);②HDCP孕妇眼动脉的PI、RI值明显低于正常孕妇(P<0.05),而B/A值则明显升高(P<0.05);③HDCP孕妇眼底病变程度与PI、RI及B/A值显著相关(P<0.001),眼底病变越严重,PI、RI值越低,而B/A值越高:④眼底改变程度与临床病情严重程度显著相关(P<0.001)。结论:检测孕妇眼动脉的血流参数结合其眼底病变情况对HDCP的临床诊断及治疗具有明显的参考意义。
Objective: To observe the correlation between color Doppler ultrasound in detecting ophthalmic artery blood flow parameters of pregnant women and ocular fundus lesions in pregnancy-induced hypertension (HDCP) and discuss its value in the diagnosis and treatment of HDCP. Methods: Forty cases of normal pregnant women were used as the control group. The indexes of ocular arterial pulsatility index (PI), resistance index (RI) and the second peak of systolic phase (B) in 73 HDCP pregnant women were compared with the first peak (A) / A); at the same time check the two groups of fundus changes, compared different degrees of ocular fundus arterial flow parameters. Results: ① The PI and RI values of ophthalmic artery were not significantly correlated with the age and gestational age (P> 0.05), but the B / A value was significantly correlated with the age of pregnant women (P <0.001) (P <0.05), but the RI value was significantly lower than that of normal pregnant women (P <0.05), while B / A value was significantly increased (P <0.05); ③The degree of fundus lesions in HDCP pregnant women was significantly correlated with PI, RI and B / The more severe the fundus lesions, the lower the PI and RI values and the higher the B / A value. The degree of fundus change was significantly correlated with the severity of the clinical condition (P <0.001). Conclusion: Detecting the ophthalmic artery blood flow parameters in pregnant women with their fundus lesions has obvious reference value for the clinical diagnosis and treatment of HDCP.