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目的 了解年龄≤ 45岁不稳定心绞痛 (UA)或非ST段抬高心肌梗死 (NSTEMI)住院患者的冠状动脉造影和临床特征。方法 SUNDAY注册研究为单中心回顾性登记研究 ,选择首次因UA/NSTEMI在我院住院的患者 ,按年龄分为≤ 45岁和 >45岁组 ,分析其冠状动脉造影 (CAG)和临床特征。结果 共入选 10 13例患者 ,其中≤ 45岁的患者 72例 ( 7.1% )。年龄≤ 45岁组男性更多( 93 .1%与 68.7% ,P <0 .0 0 1) ,吸烟比例较高 ( 5 9.7%与 3 6.7% ,P <0 .0 0 1) ,而高密度脂蛋白胆固醇(HDL C)较低 ( 3 7.0 4± 7.80mmol/L与 40 .48± 9.3 5mmol/L ,P <0 .0 1) ,高血压 ( 3 6.1%与 65 .4% ,P <0 .0 0 1)、糖尿病 ( 9.7%与 2 1.3 % ,P <0 .0 1)和缺血性卒中 ( 0 %与 9.1% ,P <0 .0 1)病史少。年龄≤ 45岁的患者单支病变更多 ( 4 4.8%与 2 8.4% ,P <0 .0 1)。结论 年龄≤ 45岁UA/NSTEMI的住院患者中男性和单支病变更多 ,吸烟比率更高 ,HDL C更低
Objective To investigate the coronary angiography and clinical features of hospitalized patients aged ≤ 45 years with unstable angina (UA) or non-ST-segment elevation myocardial infarction (NSTEMI). Methods The SUNDAY registry was a single center retrospective registry study. Patients hospitalized for the first time in our hospital with UA / NSTEMI were enrolled in this study. Their coronary artery angiography (CAG) and clinical features were analyzed by age group 45 years or younger than 45 years. Results A total of 1013 patients were enrolled, including 72 (7.1%) patients ≤ 45 years of age. There were more males (93.1% vs 68.7%, P <0.001) and higher rates of smoking (57.7% vs 37.7%, P <0.001) for patients 45 years of age or younger HDL C was lower (3 7.0 4 ± 7.80 mmol / L vs. 40.48 ± 9.3 5 mmol / L, P <0.01), hypertension (6.1 6.1% vs 65.4%, P <0 0 01), diabetes (9.7% vs 21.3%, P <0.01) and ischemic stroke (0% vs 9.1%, P <0 01). Patients younger than 45 years had more single-vessel lesions (4.8% vs 8.4%, P <0.01). Conclusions In-patients with age ≤ 45 years of UA / NSTEMI have more male and single lesions, higher rates of smoking, and lower HDL C