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目的分析以黄疸为主要表现的婴儿败血症的临床特点及病原学检查结果和药物敏感情况,指导临床治疗。方法对30例败血症患儿的起病情况、细菌培养和药物敏感实验进行分析。结果临床特点30例中因黄疸就诊15例,其它就诊原因有发热2例,纳差、吐奶、嗜睡2例,脐部脓液、渗血2例,臀红2例,脓疱疮1例,颈部褶烂1例,鹅口疮1例,咳嗽鼻塞2例,腹泻2例。培养细菌以葡萄球菌为主,其中表皮葡萄球菌(46.7%)和金黄色葡萄球菌(20.0%)占前2位;检出菌大多数对万古霉素敏感(93.8%),其次是克林霉素(50.0%)。结论对以黄疸为主要临床表现的患儿应早期行血培养检查,对可疑为败血症的患儿,早期以经验用药为主,并结合本地区近年病原菌及耐药特点,合理应用,待血培养检出细菌后,再根据药敏调整治疗方案。
Objective To analyze the clinical characteristics of infant sepsis with jaundice as its main manifestation and the results of pathogen test and drug sensitivity to guide the clinical treatment. Methods Thirty cases of sepsis in children with onset, bacterial culture and drug-sensitive experiments were analyzed. Results The clinical features of 30 cases of jaundice treatment in 15 cases, the other treatment for fever in 2 cases, anorexia, spit milk, drowsiness in 2 cases, umbilical pus, bleeding in 2 cases, hip red in 2 cases, impetigo in 1 case, 1 case of neck folds, 1 case of thrush, 2 cases of cough and nasal congestion, 2 cases of diarrhea. Staphylococcus aureus (46.7%) and Staphylococcus aureus (20.0%) accounted for the top two. Staphylococcus aureus was most sensitive to vancomycin (93.8% Prime (50.0%). Conclusions Children with jaundice as the main clinical manifestation should undergo early blood culture examination. For suspicious sepsis children, early adoptive experience should be given priority to. In combination with the characteristics of pathogens and drug resistance in recent years in this area, Detection of bacteria, and then adjust the treatment plan based on drug sensitivity.