药物与环糊精(CD)复合能提高其溶解度、溶出度和生物利用度,而生物利用度的提高乃药物与CD复合使药物的溶解度和溶出度增大所致,然而,膜常会阻止复合物中药物的吸收,因为只有游离药物才能被吸收,因此稳定常数大的药物-CD复合物不利于生物利用度的提高。本文采用DL-苯丙氨酸作为竞争剂,由 Drugs and cyclodextrins (CD) complex can improve its solubility, dissolution and bioavailability, while the increase of bioavailability is the drug and CD complex drug solubility and dissolution increased, however, the membrane often prevent the complex Absorption of substances in the drug, because only free drugs can be absorbed, so the stability of large drug -CD compound is not conducive to the improvement of bioavailability. This article uses DL-phenylalanine as a competitor, from