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器官移植者,由于接受免疫抑制剂易患包括真菌在内的各种感染。作者对1967～1988年中110例131次肾移植手术的感染者作了回顾性研究。110例共131次肾移植中,供肾来源89次为尸体肾,42次为亲属肾。1981年前使用的免疫抑制剂是硫唑嘌呤和皮质类固醇,部分病例合并应用抗淋巴细胞球蛋白;1982年后为环孢菌素合并应用半量的皮质类固醇。本组110例中57例共发生81次感染,其中28例死于感染,占25.5%。81次感染中能确定致病菌的
Organ transplants, due to immunosuppressive agents susceptible to various infections, including fungi. The authors retrospectively studied 110 cases of 131 renal transplant recipients from 1967 to 1988. A total of 131 cases of kidney transplantation in 110 cases, 89 for the renal cadaveric renal origin, 42 relatives of the kidney. Immunosuppressive agents used before 1981 were azathioprine and corticosteroids, some cases combined with anti-lymphocyte globulin; after 1982 for the cyclosporin combined with a half amount of corticosteroids. The group of 110 cases of 57 cases occurred a total of 81 infections, 28 of them died of infection, accounting for 25.5%. 81 infections can identify pathogens