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Barrett食管(barrett′esophagus,BE)s与食管腺癌(esophageal adenocarcinoma,EA)的发生密切相关,近年来二者的发生率逐渐升高,关于BE及EA发生的确切机制目前尚不清楚。肿瘤是一个多基因参与的与细胞周期紊乱和凋亡受阻密切相关的疾病。Survivin是近年来新发现的一种凋亡抑制因子,属于凋亡抑制蛋白
Barrett’s esophagus (BE) s is closely related to the occurrence of esophageal adenocarcinoma (EA). The incidence of Barrett’s esophagus (BE) and esophageal adenocarcinoma has been gradually increased in recent years. The exact mechanism of BE and EA is not yet clear. Tumor is a multi-gene involved in the cell cycle disorders and apoptosis are closely related to the disease. Survivin is a new inhibitor of apoptosis found in recent years and belongs to the apoptosis-inhibitory protein