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目的探讨间苯三酚静脉注射配合徒手扩张宫颈缩短产程的效果。方法将240例初产妇随机分为3组各80例。分娩过程中待宫口开大3cm时,观察组采用间苯三酚80mg静脉注射配合徒手扩张宫颈口;对照1组用地西泮10mg缓慢静脉注射,不扩张宫颈口;对照2组用间苯三酚80mg静脉注射,不扩张宫颈口。比较三组产妇分娩时总产程时间、产后出血量、新生儿窒息及剖宫产率。结果观察组产妇总产程时间、新生儿窒息与对照1组及对照2组比较,差异有显著性意义(P<0.05,P<0.01);剖宫产率较对照1、2组显著下降(P<0.05,P<0.01);3组产后出血量比较,差异无显著性意义(均P>0.05),对照1组药物不良反应发生率显著高于观察组及对照2组(均P<0.01)。结论静脉注射间苯三酚配合徒手扩张宫颈能加速产妇宫颈口扩张,缩短产程,而且对母婴安全无显著不良影响。
Objective To investigate the effect of phloroglucinol intravenous injection combined with bare hand expansion of the cervix to shorten the labor process. Methods 240 cases of primipara were randomly divided into three groups of 80 cases. During labor, when the cervix was opened for 3 cm, the observation group received intravenous injection of 80 mg phloroglucinol for unilateral expansion of the cervix; the control group 1 received slow intravenous injection of diazepam 10 mg and did not dilate the cervix; and the control group 2, Phenol 80mg intravenous injection, does not expand the cervix. Three groups of maternal labor time of labor, postpartum hemorrhage, neonatal asphyxia and cesarean section rate were compared. Results Compared with control group 1 and control group 2, there was significant difference between the observation group and the control group (P <0.05, P <0.01). The rate of cesarean section was significantly lower than that of the control group 1 and 2 <0.05, P <0.01). There was no significant difference in the amount of postpartum hemorrhage among the three groups (all P> 0.05). The incidence of adverse drug reactions in the control group 1 was significantly higher than that in the observation group and the control group (P <0.01) . Conclusion Intravenous injection of phloroglucinol together with bare hands dilating the cervix can accelerate maternal cervical dilatation and shorten the birth process, but also have no significant adverse effects on maternal and infant safety.