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目的:回顾分析颌面颈部恶性淋巴瘤的临床特点,治疗和预后。方法:对163例颌面颈部恶性淋巴瘤患者的临床资料及随访情况进行回顾性研究。结果:恶性淋巴瘤163例中,男:女=1.86:1,中位年龄43.2岁。发病部位依次为颈部,腭部,腮腺及牙龈,首次就诊误诊率47.9％。主要采用单纯化疗及综合治疗。随访病人存活时间超过10年8例,超过5年31例,死亡病例平均存活20.6月,中位生存期为12个月。结论:颈部恶性淋巴瘤首诊中易被误诊;组织活检以明确诊断并制定相应的治疗计划至关重要;化疗及综合治疗是本病的主要治疗手段。
Objective: To retrospectively analyze the clinical characteristics, treatment and prognosis of maxillofacial and cervical malignant lymphoma. Methods: The clinical data and follow-up of 163 patients with maxillofacial and neck lymphoma were retrospectively studied. Results: 163 cases of malignant lymphoma, male: female = 1.86: 1, the median age of 43.2 years old. The incidence of sites followed by the neck, palate, parotid and gingiva, the first visit misdiagnosis rate of 47.9%. The main use of chemotherapy and comprehensive treatment. Follow-up Patients survived for more than 10 years in 8 cases, more than 5 years in 31 cases, the average survival of deaths 20.6 months, the median survival was 12 months. Conclusion: The first diagnosis of malignant lymphoma in the neck is easily misdiagnosed; tissue biopsy to confirm the diagnosis and to develop the appropriate treatment plan is essential; chemotherapy and comprehensive treatment of the disease is the main treatment.