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青蒿素(1)是青蒿的抗疟有效成分。它是一个由过氧基团组成缩酮的新倍半萜内酯。本文报道按图式1所示的1以及脱氧青蒿素(2)的立体控制合成。烯醇甲醚酮酸甲酯3是合成的
Artemisinin (1) is the effective antimalarial component of Artemisia annua. It is a new anthraquinone lactone from a peroxy group. This paper reports the stereoselective synthesis of 1 and deoxy artemisinin (2) as shown in Scheme 1. Methyl vinyl ether methyl ether 3 was synthesized