癫痫是神经科常见的一组慢性疾患 ,其发病机制极其复杂 ,但最后通路不外是脑内兴奋与抑制失去平衡 ,导致大脑神经元异常放电所致。因此 ,有关癫痫机制的研究大多集中在探索引起神经元异常放电的上游分子 ,如谷氨酸、神经肽和一氧化氮等。而对神经元异常放电的物质基础———离 Epilepsy is a group of neurological common chronic diseases, the pathogenesis is extremely complicated, but the final pathway is nothing more than brain imbalance between excitement and inhibition, leading to abnormal discharge of cerebral neurons. Therefore, the research on epilepsy mechanism mostly focuses on exploring the upstream molecules that cause abnormal discharge of neurons, such as glutamate, neuropeptide and nitric oxide. The abnormal discharge of neurons material basis --- away from